Introduction

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注is a very important pharmaceutical equipment used in the process of fast wet mixing, homogenization, humidification, and powder granulating. Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator plays an important role in thebeplay体育最新下载of solid dosage forms.

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注connects with a downstream equipmentbepaly下载app 形成闭合造粒。

However, despite the numerous importance of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator, a lot of people are quite unfamiliar with this equipment.

因此，at.Senieer, we have written this comprehensive guide to provide an answer to any questions you may want to ask aboutRapid Mixer Granulator (RMG) or the High Shear Mixer Granulator.We believe you will find this ultimate guide to快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注对你很有用。

您可以在动作中看到我们的快速混频器造粒机（RMG）或高剪切搅拌机造粒机bepaly娱乐投注这里

Whether you are looking for abepaly娱乐投注高剪切搅拌机出售或者你需要最好的homogenizer mixerfor your pharmaceuticalwet granulation流程，您将在此终极指南中找到所有必要的信息。

我们在此终极指南中涵盖的一些主题快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注include:

• 高剪切搅拌机的热门制造商bepaly娱乐投注
• 快速混合器造粒机（RMG）或高剪切搅拌机造粒机的类型bepaly娱乐投注
• 造粒方法和过程监测
• 湿造粒过程
• Advantages and Disadvantages of powder mixer machine
• 如何选择最佳的快速混合器造粒机（RMG）或高剪切搅拌机造粒机bepaly娱乐投注
• 向美国，欧洲，加拿大等国家运输高剪切混合bepaly娱乐投注器的方法
• Frequently Asked Questions on High Shear Mixer

Chapter 1: Description of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator

Are you interested in buying快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注, but you have never been changed to see the均质机器？

在这里，我们向您展示快速混合器造粒机（RMG）或高剪切搅拌机造粒机的描述。bepaly娱乐投注

However, before we dive into that, let’s quickly check the definition of granulation.

What is granulation?

Granulation involves the process of gathering particles together through the creation of bonds between them.

在制粒过程中产生键，使用结合剂或压缩。

快速混合器造粒机（RMG）或高剪切搅拌机造粒机做了什么？bepaly娱乐投注

Also called homogenizer or mixing machine, Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator is pharmaceutical equipment that transports or disperses a section or ingredient which can be solid, liquid or gas. The ingredient is transported into a primary continuous liquid section that is usually incompatible.

快速混合器造粒机（RMG）或高剪切搅拌机造粒机及其功能的零件bepaly娱乐投注

Senieer Shear Mixer mainly contains a loading system, impeller system, spray system, chopper system,锥磨坊（作为可选项目）system, control system, etc.

A rotor or vein along with the stationary mechanical device. Also, the fixed part can be an associate array of stators and rotors. The device is engaged with a tank containing the ingredients to be mixed.

将管道通过成分的通过以形成剪切。快速混合器造粒机（RMG）或高剪切混合器造粒机产生可用于制药公司的粒状产bepaly娱乐投注品。

其他类型的高剪切混合器可以产生悬浮液（bepaly娱乐投注分布在液体中的气体）以及乳液。除药剂外，还可以在其他行业中使用造粒过程的结果。

Senieer快速混合器造粒机（RMG）或高剪切搅拌机造粒机也广泛用于保健品，食bepaly娱乐投注品，化妆品，化学，化妆品行业和衍生自同质化，乳化，粒度减小和分散的粘合剂。

在高剪切混合器bepaly娱乐投注造粒工艺中，需要固体部分。流体或溶液用于作为有助于该过程的助理。

After the solid part has been formed, it is chopped down to the needed particle size which is subsequently passed to the drying bed.

From the drying bed, the fluid is completely removed to form granulated products.

混合机或快速混合器造粒机（RMG）或高剪切搅拌机造粒机的特点bepaly娱乐投注

该设备设计精美吸引the eye. There are various product types and designs from different manufacturers of Rapid Mixer Granulator (RMG) or the High Shear Mixer Granulator.

但是，Senieer的所有设计都遵循当前的良好制造实践合规（CGMP）和美国FDA。

Also, our Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator carries out the automated mixing and granulating process using a single bowl.

Another superior feature of Senieer highs shear mixer granulator is the extremely high precision mixing and Short Batch Time for granulation coupled with easy to clean and residue-free discharge of granules,真空输送material（作为可选项目）可在您的要求提供。

We also have exclusive design spotting a three mixing impeller and also blade angle used in forceful pushing out products.

对于cutting lumps and turning out granules, our high Shear mixer has a sturdily built chopper blade that seamlessly takes care of the process.

The Senieer mixer also features dual speed mixing impeller and an intensive chopper for mixing and granulating respectively.

Electro-pneumatically operated flush-fitting discharge plug and air pursing seal for the two shafts that come with it.

Senieer快速搅拌制粒机(RMG)或高剪切Mixer Granulator is easily controlled, thanks to the PLC and the huge HMI touch screen.

It also has an advanced heating and cooling mechanism with the product bowl jacketing（作为可选项目），加热介质根据您的要求（水或油），以及真空的混合过程。

The impeller and chopper rocks variable speed drive.

You can charge the material by vacuum or by manual.

您可以通过使用蠕动泵，气动膜片泵和压力罐喷涂系统来添加粘合剂，根据您的工艺和容量要求，齿轮齿轮，同时存在阻燃电动机到位。

快速混合器造粒机（RMG）或高剪切搅拌机造粒机安全特征bepaly娱乐投注

采用高级剪刀搅拌机造粒机，您可以确保具有足够特征的最佳安全性。

Open bowl cover state, impeller and chopper can’t work, there is logical protection.

它具有封闭的总驱动传动系统，其限位开关顶盖安装在操作期间以防止盖子的意外开口引导。自动的

此外，安装压力开关，以确保设备中的最佳压力。

有紧急停止按钮和过载继电器保护，以防止使用过程中的事故。

Also, an explosion-proof system（作为可选项目）可在您的要求提供。The explosion-proof design includes an explosion-proof touch screen, explosion-proof junction box, explosion-proof winding tube, explosion-proof motor.

Production Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator parts: WIPs system is an optional item of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator; it can share one set of WIP system with fluid bed equipment.

Chapter 2: Types of Inline mixers or High Shear Mixer Granulator

如果您正在寻找存在的各种类型的快速混合器造粒机（RMG）或存在的高剪切混合器造粒机S，则可能会发现难以选择选择哪一个。bepaly娱乐投注

然而，作为您通过选择最佳高剪切均质器的过程的伴侣，参赛者提供了一些因素，您必须考虑选择最佳类型的工业或制药需求的混合设备。

The dosing system types

Ensure to check the dosing system type that is in place in your granulator machine. Is it a manual or automatic system? Does it include a binding solution or powder dosing system? Whichever works for you is what you should go for. Nevertheless, you have to put in mind the purpose of purchasing the mixer machine in the first place.

The impeller blade design

造粒工艺效率由叶轮叶片携带的设计确定。典型的均化器混合器主要具有不同数量的刀片，其可以在一些造粒机中最多三个。您需要考虑的另一个因素是叶轮叶片的设计和位置，因为它们具有同样具有重要意义。

通常，在快速混合器造粒机（RMG）或高剪切混合器造粒机中，叶轮尖端的位置是横向的，以便于bepaly娱乐投注降低死点的可能性。叶轮的功能是混合和形成颗粒。

Also, the rotation speed of the homogenized mixer depends on the specification of the machine including the design.

Position of the impeller

快速混合器造粒机（RMG）或高剪切搅拌机造粒机S.bepaly娱乐投注are classified based on usage; there is a laboratory-style of the high shear mixer and the production style.

Laboratory style快速混合器造粒机（RMG）或高剪切搅拌机造粒机S.bepaly娱乐投注are primarily used in the homogenization of the ingredients used in making different drugs and granules in the pharmaceutical industry.

Production style Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator son the other hand are used in the manufacturing industries. Mixing of ingredients used in making granules.

Senieer has Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator s which are effective as mixer machines in both laboratory and industrial uses.

Chapter 3: How Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator Works

Are you interested in how high shear mixer works? The technology behind the high shear mixer is complex and fascinating.

Regardless of the brand, you are choosing, high shear homogenizers follow similar approach om carrying out their granulation operation.

The working principle of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator follow the following processes;

Mixing of the powder

The high shear granulation process starts with the mixing of the powder in a bowl using the impeller.

Addition of binder or granulation liquid

接下来，叶轮前进以混合并在5RPM-300rpm之间的速度下施加成粘合剂的造粒液体

Dampening or wetting of the powder

快速混合器造粒机（RMG）或高剪切混合器造粒机部分，切碎机断开湿块以产生bepaly娱乐投注200-3000rpm的速度产生颗粒。

Nucleation process (formation of crystals powder)

At this stage, you will notice the formation of crystal powder otherwise called the nucleation process.

Granule growth and densification of powder

通过使用高功率每单位质量将造粒流体掺入粉末中，颗粒或功率致密化的凝聚发生。通过高剪切力的旋转来实现该过程。

Breakage and attrition of granule

造粒过程以颗粒的破损和磨损结束，然后将其转移到需要药物目的或其他工业用途的任何地方。

Chapter 4: High Shear Mixer Wet Granulation Process Guide

我们将研究湿造粒过程。您可以放心，本章将回答有关高剪切混合器的湿造粒过程的所有问题。bepaly娱乐投注我们将检查您可能拥有的一些问题，如：使用快速混频器造粒机（RMG）或高剪切搅拌机造粒机时可能遇到的问题是什么？bepaly娱乐投注如何在高剪切造粒机中平衡实验室高剪切机械机的成功测试，以及高剪切造粒机的生产失败？在实验室湿造粒过程扩增期间，您可以遇到的困难是什么？本章涵盖了湿造粒设备等区域，以及如何将湿造粒过程掌握为使用者或制药设备的操作员。有几个因素可以影响湿造粒过程特别是在扩增期间的连接。

What you should know about the wet granulation process

首先，重要的是要注意，湿造粒方法主要发生在固体剂型中。

Senieer，中国高剪切搅拌机的领先供应商可确保R＆D高剪切搅拌机提供给bepaly娱乐投注将水平快速混合器造粒机（RMG）或高剪切搅拌机造粒机出售的可扩展性。

实验室高剪切混合器的部分bepaly娱乐投注

You may be interested in knowing the parts that make laboratory high shear functional. We have highlighted some of the crucial parts, they include;

Senieer GLS Laboratory High Shear Mixer

• Impeller: the impeller is unique and highly functional
• 砍刀: it comes in compact assembly, and the arrangement is very easy to remove
• 直接驱动系统: this enhances the productivity of the Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator
• Interchangeable bowl：这是可根据要求提供的，转换时间为5-7分钟。随着时间的推移而变化，将可以进行混合设备进行处理
• Electric and pneumatic panel: features easy-to-access panels that guarantee safety during the wet granulation process.

• 

https://www.researchgate.net/publication/275518904_Improved_Tablet_Production_by_Modified_Granulation_Techniques-A_Review/figures?lo=1&utm_source=google&utm_medium=organic

Senieer始终处于与快速混合器造粒机（RMG）或高剪切混合器造粒机的可信制造商合作的最前沿，用于创新设计，可增强固体剂量生产。bepaly娱乐投注这有助于实现顶级缺口的药物制造业务。我们还可以测试您的过程为您的快速混频器造粒机（RMG）或高剪切搅拌器造粒机进行定制设计。bepaly娱乐投注

Raw materials are converted into final dosage forms in development, pilot, clinical and production volumes using wet granulation in one continuous granulation line.

Senieer快速搅拌制粒机(RMG)或高剪切Mixer Granulator also named high shear mixer, homogenized mixer or rapid mixer granulator offers the outstanding advantages of efficiency and product uniformity achieved with High Shear Mixers.

Senieer shear mixer granulators include GL Series lab high shear mixer, GLS high shear granulation, and GM Series rapid mixer Granulators.

Model		GL-100	GL-200	GL-300	GL-400	GL-500	GL-600.	GL- 800
料斗体积（L）		100	200	30.0	400	500	600	800
Effective volume(L)		40-80	80-160	120-240	160-320	200-400	240-480	320-640
喂养量（kg）		20-40	40-80	60-120	80-160	100-200	120-240	160-320
Mixing rotation speed(rpm)		28-280	22.-220	20-200	18-152	17-169	15.-155	15.-158
Cutting rotation speed(rpm)		30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900
Mixing power(kW)		11.	18.5	22.	30.	37.	45.	55.
Cutting power(kW)		4	4	5.5	5.5	7.5	11.	15.
Compressed air	（Mpa) Pressure	0.4-0.6	0.4-0.6	0.4-0.6	0.4-0.6	0.4-0.6	0.4-0.6	0.4-0.6
	(M3/min) Consumption	0.2-0.8	0.2-0.8	0.2-0.8	0.2-1.1.	0.2-1.1.	0.2-1.5	0.2-1.5

Model		GM-100	GM-200	GM-300	GM-400	GM-500	GM-600	GM-800
料斗体积（L）		100	200	30.0	400	500	600	800
Effective volume(L)		40-80	80-160	120-240	160-320	200-400	240-480	320-640
喂养量（kg）		20-40	40-80	60-120	80-160	100-200	120-240	160-320
Mixing rotation speed(rpm)		28-280	22.-220	20-200	18-152	17-169	15.-155	15.-158
Cutting rotation speed(rpm)		30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900	30.0-2900
轧机转速（RPM）		200-900	200-900	200-900	200-900	200-900	200-900	200-900
Mixing power(kW)		11.	18.5	22.	30.	37.	45.	55.
Cutting power(kW)		4	4	5.5	5.5	7.5	11.	15.
轧机力量（kw）		2.2	2.2	2.2	2.2	3	3	3
Compressed air	Pressure(Mpa)	0.4-0.6	0.4-0.6	0.4-0.6	0.4 – 0.6	0.4-0.6	0.4-0.6	0.4-0.6
	消费（M3 / min）	0.2-0.8	0.2-0.8	0.2-0.8	0.2-1.1.	0.2-1.1.	0.2-1.5	0.2-1.5

快速造粒机搅拌机整体集由装载系统，叶轮系统，喷雾系统，斩波系统，湿锥磨机系统组成(as an optional item），控制系统等

Senieer high shear mixers’ chopper ensures an optimum granular structure, the GM series Rapid Mixer Granulator (RMG), or the High Shear Mixer Granulator equipped with a chopper and high straight shear mixing blades.

斩波器在工作容器的下三分之一的位置导致其非常高的效率，即使存在最小填充体积。

Senieer shear mixer granulator rapid mixer’s chopper exists in two speed or variable speed.

主轴和斩波器轴设计有单向流动空气密封，流量，空气密封的压力可以测量和控制，以防止和检测进入内部的粉末或水。

Senieer super mixer auto controls stop position of the impeller; auto elevates the main shaft pneumatically for the visible check without dismantling.

湿造粒中的全部重要工具是底部驱动的Z转子。Z转子的独特几何形状可确保最大效率，同时最小化所需的电源。

尖端测量和制造工艺确保转子和工作碗的底部之间的间隙保持在最小，同时最大化产品产量。

Senieer Unique technology guarantees ease of handling.

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注rapid has good quality at affordable prices in China.

如果您想启动湿造粒设备业务，请联系我们for more details, we will send you all quotations for machines, and drawing.

We can customize all your equipment based on your requirements. Once you approve the detailed user requirement statement (URS), we can supply the Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator drawing and suggestion for your factory layout.

此外，我们提供了我们的技术支持，为您的流程和布局提供定制设计。

无论是来自实验室快速搅拌机造粒机（RMG）或高剪切搅拌机造粒机设备还是放大批次高剪切搅拌机设备，普遍已知它难以设计和放大。bepaly娱乐投注

这是因为湿造粒机中的许多工艺参数和竞争机制。

Also, the production batch Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator equipment and existing production high shear mixer equipment to larger production Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator equipment design is demanding too.

Why difficult from R&D high shear mixer to amplifying batch Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator?

高剪切湿法制粒是液体粘合剂的细粉的造粒。当将粘合剂加入造粒碗中时，湿造粒机的叶轮和斩波器开始剪切以形成特定的性质 - 颗粒，包括粒度，颗粒强度，溶解，可压缩性和含量均匀性。

To achieve the desired particle properties, several granulation parameters need to be optimized, including the size and geometry of the granulator, the speed of the impeller, the speed of the chopper, the mode of addition of the binder, the flow rate, and the granulation time.

The traditional wet granulation process is a method of the gradual enlargement and problem finding.

改变造粒机的参数以各种方式影响颗粒的性质。

Without understanding the principle of amplification, you will encounter changes in all variables.

颗粒形成过程涉及三个阶段：成核生长, and母细胞核的生长, andrupture.

成核被认为是造粒的开始，包括形成基本颗粒，也称为母细胞核。

In high shear wet granulation, the mother nucleus is formed at the stage where the liquid is in contact with the powder bed and the internal reaction of the powder particles.
母细胞核的生长是由于粉末颗粒粘附到母细胞核的表面或两种或更多种颗粒的组合。这一步通常也使粒子更密集。

当粒状碗中的力（剪切力，来自叶轮，斩波或造粒壁的力）超过颗粒强度时，颗粒被破坏。

改变上述参数可以改变粒子的产量和性质。下面将给出关于如何控制肉芽参数的一些建议和评论。

How to control granulation parameters?

Granulator geometry

Many companies do not control the geometry of the high shear mixer, but the laboratory Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator equipment is preferably selected or designed to be similar to the device with the same geometry, i.e., the same aspect ratio.

具有类似geometr放大设备之间ic structures is equivalent to amplifying only the stirring impeller speed, which is much simpler. It is also essential to amplify the speed of the impeller.

搅拌叶轮旋转速度对粒度的影响主要与制剂的组成特性和该方法的造粒机制有关。

在一些情况下，增加叶轮的速度可以增加粒度。在一些情况下，增加叶轮的速度会增加颗粒的破损率，导致颗粒的减少。
The most important thing is to consider the air intake assembly of the high shear mixer.

During the operation of many granulators, the internal particles appear twisted rope, and the powder bed moves in a circular shape in the granulating pot under the action of the air system.

If the stirring impeller rotation speed is too low, the inside of the granulating bowl will be in a bumping state, so that the surface movement of the powder bed layer is relatively slow, and only the bumping state caused by the stirring impeller rotation speed is obtained.

The twisted rope state is vital for the mixing of the powder in the granulating pot and the distribution of the liquid, and mainly affects the size of the mother nucleus. There have been some laws for the amplification of the stirring impeller speed. Some people advocate a constant linear velocity.

有些人认为弗劳德数(ratio of centrifugal force to gravity inside the high shear mixer) is constant. Others have suggested using a continuous shear force inside the granulator, and they recommend using the following formula when zooming in NDn Where N is the angular velocity of the impeller, D is the diameter of the paddle, and n is a constant (n is found to be equal to 0.85, although this value is likely to be prescription-system dependent)

·砍刀speed

快速混合器造粒机（RMG）或高剪切混合器造粒机斩波器的作用不是很清楚。bepaly娱乐投注基于大多数混合物的性质，我们发现它既不促进质量的生长，增加质量的紧凑性，或破坏颗粒。

增加剪切混合器造粒机的尺寸可以降低颗粒和斩波器之间的相互作用的频率。在这种情况下，在放大过程中固定切割刀片的线性速度是一个很好的想法，因为颗粒类似地受到影响。

However, if other variables in the amplification process cause the particles to increase, increasing the chopper speed can reduce the size of the particles.

如何添加粘合剂和流速

一些先进的粒子研究已经致力于开发母核状态图，该核心态图描述了在给定的造粒过程下的成核过程中。该地图有两个无量纲参数：液滴进入的时间粉末床and喷射流量(which can be considered as the ratio of the liquid spray rate to the tumbling speed of the bed surface particles).

The droplets enter the powder bed for a short period (i.e., droplets that quickly enter the powder bed) and low jet flow (i.e., the droplets can be sprayed well onto the powder surface), and their nucleation behavior is controlled by droplets. That is to say, many mother cores are formed by a single droplet, and the size range of the mother core is relatively narrow. Either the time of droplets entering the bed increases or the increase of the spray flow rate leads to over-wetting.

The liquid deposits on the surface of the powder bed to form a large mother nucleus. In this case, mechanical force is required to destroy it. Force destruction leads to a wide distribution of the size of the mother nucleus. The size distribution of the nucleus is the beginning of granulation. For many prescriptions, it is critical to forming a similar size nucleus through the granulator. If the amplification process is to achieve the state in which the mother core is controlled by the droplets, it is required that the droplet size during the amplification process is the same as the droplet size during the small test (the time when the droplet enters the powder bed is similar).

Also, the low discharge flow rate is necessary (formation of a single sheet) for the droplet mother core to be effective. The method of reducing the spray flow rate is to ensure that the spray width covers the effective surface of the bed (i.e., the radius of the granulator). This is to reduce the volume flow rate of the adhesive and increase the tumbling speed of the powder during the process of wet granulation in a high shear mixer.

造粒时间：难以通过不同的造粒机确定造粒时间对颗粒性质的影响。液体粘合剂在尺寸的造粒罐中的机械分布需要巨大的时间。然而，这主要与配方和工艺参数有关。

下面的公式可以放大造粒时间：Tx / Ty =（Sx / Sy）（Vx / vy）其中，x是造粒碗放大前，Y是扩大的造粒壶，Tx，Ty是肉芽造粒时间，sx，sY是造粒壶的内表面积，VY是造粒壶体积。

无论如何，有很多因素控制参数，超出了我们上面写的。

That is why you should review the technology behind D&R high shear mixer and manufacturing high shear mixer to know more about the high shear mixer.

Through theory and technical parameter specifications, I believe you have learned a lot about the high shear mixer, especially the reason for the difficulty in R&D high shear mixer to amplifying batch Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator.

Senieer focus on research about technology, special combines machinery, and process which are key components from importation to production.

Thus, Senieer as a global high shear mixer rapid granulator mixer manufacturer and supplier is well versed in the sales and supply of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator.

At Senieer, we are committed to providing you quality products as we are concerned about building our brand.

As such, we appreciate the feedback from you, not only in the aspect of reviews on machinery you purchase from us alone but also in our entire work process. They help us improve in all phases of our operation; from customer service to aftersales maintenance.

第5章：影响快速混合器造粒机（RMG）或高剪切混合器造粒机的造粒工艺和优点的因素bepaly娱乐投注

Many factors can affect the granulation process of a high shear mixer. If you are not quite familiar with how this homogenizer mixer works, you can find it difficult to know how to best make use of it.

如果您希望最大限度地提高高搅拌机的生产率，我们突出了一些要注意的因素。他们包括;

• • • Formulation variables

The type and amount of binders used as an inactive material during the granulation process will go a long way in affecting the entire granulation process.

• • • 成分的物理性质

待造粒的材料的物理性质可以在影响造粒过程方面发挥巨大作用。应考虑尺寸，硬度和材料的性质等物理性质。

• • • Binder Materials

There are several binder materials and solutions that you can use. Some of the popular excipients or binder materials used for Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator include starch paste, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polypropylene pyrrolidone, etc.

天然粘合剂：纤维素，金合欢，明胶，淀粉糊，藻酸，葡萄状和预胶质化淀粉

糖: Liquid glucose, sucrose

Synthetic and Semisynthetic Polymers：乙基纤维素，羟基丙基纤维素，羟基丙基甲基纤维素（HPMC），甲基纤维素，聚乙烯醇，聚乙二醇（PEG）和聚乙烯吡咯烷酮（PVP）。

• • • 过程变量

These include all the variables that can affect the outcome of the granulation process. Listed below are some of these process variables;

1. 砍刀speed
2. Designs of Granulator

• • • 添加一个制粒的方法解决方案

1. Rate of granulating solution
2. Speed of Impeller
3. Granulator bowl load

• • • Wet-massing tire

Advantages of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator s

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注has several advantages of mixing equipment with low shear. Some of the benefits include;

• Granulation of highly cohesive materials that contain hydrophilic polymers. Such granulation cannot be derived from low shear
• 在高剪切造粒中，与低剪切相比，整个造粒过程需要较短的时间
• 只需要少数粘合剂，有助于将生产成本保持在最小水平。
• 由于高剪切造粒过程中的粉尘产生降低，工人曝光较少的抗剪切造粒造成的灰尘
• You can predict the outcome of the granulation process when you use a high shear mixer
• 易于实现高剪切的均匀粒度分布，也可重复较小的折磨颗粒
• 您可以使用快速混合器造粒机（RMG）或高剪切搅拌机造粒机在较短的时间内实现干燥bepaly娱乐投注

第6章：如何选择最佳的快速混合器造粒机（RMG）或高剪切搅拌机造粒机bepaly娱乐投注

与其他每种设备和机器一样，选择完美的快速混合器造粒机（RMG）或贵公司的高剪切搅拌机造粒机可能是很大的挑战。bepaly娱乐投注

通常，您将遇到很多广告，以及几家公司拥抱他们的高剪切混合器的方式是切片面包后的下一个最佳发明。bepaly娱乐投注

但是，制造虚假索赔是非常容易的。它留给你作为买家从种子中转移轴。

At Senieer, we have helped you with what to look for before you spend your hard-earned money on mixing equipment that doesn’t offer you the actual value for money.

Read on as we expertly dissect the factors to consider.

·Check the Brand Reputation

Whether your business is located in United States, South Korea, Thailand, Germany, Columbia, Egypt, Indonesia, Malaysia, Pakistan, Bangladesh, Russia or Vietnam and you need quality high shear mixer for sale in China, the first thing you should check is the reputation of the brand you are dealing with.

它们可靠，灵活，具有信誉良好的耐用性吗？他们提供售后服务吗？他们的产品保修是谁可以保证他们的诚信？

The reputation of high shear mixer manufacturers partnered with can go a long way in determining how reliable their product will be.

Some companies may claim they are the best and even appear the highest in organic search, thanks to SEO. However, that is not enough as an indication. Ask for recommendations from people that have had a deal with them in time past.

Online reviews can be manipulated, thus, ensure that you do your research very well so that you don’t end up buying overpriced inferior products.

·寻求灵活性

就像多任务服务就像招募员工的一个非常有价值的技能，因此灵活地选择搅拌机。

You surely want a product that can be used across many fields such as pharmaceuticals to food, cosmetics, and other industrial application of high shear technology.

Also, you should put into consideration factors such as recipes, volume, and products — the better, the higher the level of flexibility, the better for your company.

在灵活性方面考虑的一些功能包括：

• Scalability- 无论生产量如何，都会始终如一的质量输出。
• PLC控制– The whole process control by Programmable Logic Controller. The control system is a Siemens S7-300 smart series stored program control (PLC). It features an operator panel unit of 12 inch Siemens HMI panel available on your request（作为可选项目）.

• 

为防止粘附物质，特别是在锚/叶轮下，

Service (adjustment) should be provided by one operator.

You can also control the following; Loading-Mixing time, impeller speed, chopper speed, solution feeding speed, solution feeding period, granulation period, discharging control.

There are three levels of passwords to access the panel.

互锁和警报设计在控制系统和HMI中。设计了HMI记录历史警报的具体页面。

It can be frustrating when you use mixing equipment that gives no room for prediction and control.

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注that allows you to predict and control the parameters such as the size of binder droplet and distribution of particles is best for you, and that exactly what we offer atSenieer.

多功能性 -您的公司通常会产生不同品种的产品吗？如果是，那么您应该尝试去提供多功能性的造粒设备。混合设备将拒绝您需要的特定产品;无论是西药颗粒，片剂颗粒，胶囊灌浆颗粒，用于制药或化学工业。它适用于较少的粘性颗粒。·

不同的体积– sometimes you may want to produce in batches, semi-continuous or continuous production. You should focus on Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator that ensures a seamless switch in variable volumes. This will particularly help in a situation where there is a higher demand in output without the capital to invest in new mixing equipment.

·注意细节

在每一盎司的输入计数的行业中，具有为您提供完美输出的均质混合器是必不可少的。在药物混合中，您作为药物制造商应专注于如何更好地提高生产，并尽可能地降低生产成本。选择一个高剪切混音bepaly娱乐投注器，允许您节省时间而不会影响产品质量。此外，具有降低消耗的能量的产品以及优化使用成分的产品。

·Put safety first

您的首选高剪切混合器也必须为两bepaly娱乐投注个运营商和输出提供最大保护。

• • • 操作员安全

正如我们所知道的那样，机械设备容易受到易于导致事故的故障的影响，您正在购买的快速混合器造粒机（RMG）或高剪切搅拌机造粒机必须优先考虑用户的安全。bepaly娱乐投注在危险的情况下，它必须表现出对用户的保护。这种均质混合器必须易于控制安全措施。

• • • Output Safety

Most mixing equipment will be used in the manufacturing of food and drug. As such, a very high level of safety is required. You should steer clear of any products that can tarnish your business image and brand reputation. Here are some of the factors you should look out for in your choice of Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator ;

• Effective WIP system（作为可选项目）

• 

• Proven and trackable record on safety
• FDA和EFSA被认证为食品相关材料的设备
• 符合组件供应商定期审计
• 卫生设计的搅拌机和可能ehedg批准

·选择最具成本效益

产品的价格是选择产品的重要决定因素。但是，如果不采取小心，价格可能会产生高度误导性。这是因为有时最昂贵的产品不是最好的，而最便宜可能不一定是最卑鄙的。选择最好的混音机的关键是为您提供最佳物有所值的钥匙。上面强调的输出，耐用性，灵活性和所有其他因素可以帮助您做出决定。

您可以查看此视频以查看我们的客户必须对我们说的话

https://www.youtube.com/watch?v=PA9wO4ALVp4

Chapter 7: Senieer Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator

Now that you have identified all the factors to consider in choosing the right Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator, another question to ask is, which supplier should you choose particularly when buying mixing equipment from China.

中国有许多搅拌机供应商。但是，Senieer将它们边缘。

Senieer快速搅拌制粒机(RMG)或高剪切Mixer Granulator s are reputed to be highly effective and get the job done in the lowest amount of time possible.

Senieer homogenizer mixers are fast, safe, and efficient in turning out fine particles of different sizes.

如果您是药品，化妆品，食品，健康产品，化学品或其他需要使用混合机的其他制作的制造商，那么Senieer简洁地满足您的需求。

All Senieer Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator has a perfect degree of homogenization which makes it suitable across all sectors such as pharmaceutical, health products, beauty products, and food.

已知参赛者产品精确，并产生异常高的剪切速率，使产品均匀化以导出所需的产量均匀性。

与中国和全球有信任的品牌合作，参赛者提供了尖端和精致的造粒技术，供应质量和耐用的产品，以制造和进口商相似。

Senieer快速搅拌机造粒机（RMG）或高剪切搅拌机造粒机是专门的，以提高效率bepaly娱乐投注并降低运行成本，从而节省您的时间和金钱。

If you are looking for a high shear mixer for sale that allows you to achieve a turnout of highly homogenized and uniform particle size or granule, then you have no better alternative than Senieer high shear mixer.

与其他时间的其他时间相比，您可以预测在一个无声的单个通行证中的更快且一致的输出。

作为顾客，您可以相信即将在选择右快速混合器造粒机（RMG）或高剪切搅拌机造粒机时考虑考虑的因素时，您可以自信。bepaly娱乐投注

为什么您应该选择Senieer作为您的首页供应商的快速混合器造粒机（RMG）或高剪切搅拌机造粒机bepaly娱乐投注

Regardless of the information at your disposal, you will find it challenging to select a particular Rapid Mixer Granulator (RMG) or a High Shear Mixer Granulator manufacturer that gives you the best value for money.

Senieer作为市场领导者是中国最信誉良好的高剪切制造商和供应商之一。高度评价为一站式智能制药专家，拥有30多年的供应制药和工业产品等bepaly娱乐投注,bepaly下载app ,bepaly下载ios 流体床造粒机,提升柱子products,Cone Mill,真空输送,Bin Blender., Coating machine, Clean Room System and many more.

此外，Senieer为个人和组织提供了所有药物混合设备问题的专家解决方案。

如果您正在寻找高剪切搅拌机销售，或者您需要可靠的测bepaly娱乐投注试和可信赖的药用设备供应商，特别是高剪切和其他搅拌机，Senieeris a name you can count on.

These are some of the reasons why you should patronize Senieer as your preferred high shear mixer supplier:

• • • 丰富的经验

Experience in the industry plays a crucial role in choosing a supplier for any product you want to buy. Senieer has been in the business of supplying quality pharmaceutical products in China for over 30 years.

With high-skilled and experienced personnel, Senieer has brought a revolution to the pharmaceutical equipment manufacturing and supplying in China by offering expertise advice from lab production processes and sales of quality replaceable parts.

• • • 融入创新技术

Senieer is always at the forefront of introducing an innovative solution to the pharmaceutical equipment manufacturing industry.

Senieer采用了一个创新的解决方案，适用于洁净室系统，包括洁净室，洁净室窗户，洁净室门等，您可以放心，您的设备将在最顶层功能，您无需担心。

Also, Senieer has special kinds of dust-free solid dosage formsgranulation lines对于需要吹入特殊应用的吹入创新技术的过程。

• • • 定制设计

有时，某些过程要求您绘制您需要的设备的图表，因为目的是高度特定的。在Senieer，我们帮助您通过制造满足您需求的机器来实现您的设备要求。

It takes only those who understand the process and know details to develop products that can do more than just the sum of individual components, and only a very few can match the level of skills and knowledge of Senieer in designing and fabricating customized equipment.

• • • Strong Partnership with Top Brands

Senieer的竞争优势之一是我们在全球顶级品牌形成的强大商业联盟。

At Senieer, we partner with first-class brands such as Siemens, Festo, ABB, Sefar, Schlick, Spirax Sarco, and many more to provide our customers with quality replaceable spare parts for your use.

Seamless Documentation Process

不得不经历严格的过程可以是任务和令人沮丧的。因此，Senieer确保与设备相关的所有文件都保证了在我们设备的终身期限内容的培训，运营和维护，因为制药市场等实际产业。

我们提供一整套CGMP文件，包括资格（DQ，IQ，OQ，），FAT，SAT，用户手册文档。我们按照客户请求执行资格执行。

• • • 遵守国际标准

Senieer business sections operate under the strict International Quality Standard of operation. Our control regulation certificate called the “International Quality Certifications” is ISO9001in case you want to check for confirmation.

• • • Outstanding Customer Support

At Senieer, we understand that our customers are the reasons for our existence. Thus, we prioritize giving you quality customer service. We ensure that all your requests are handled with top professionalism. Our sales representatives are courteous and pay full attention to the unique needs of our customers irrespective of the size of their request.

如果您希望将制药产品带入新的水平，请从制药公司的4.0个行业解决方案中，参赛者是您最能信任的最有能力的手。

We are more than a pharmaceutical equipment supplier; we see ourselves more as partners with the commitment to achieve success with our clients.

• Aftersales Service

It is heart-breaking to be left stranded after spending your hard-earned money on expensive equipment only for the product supplier to turn a deaf ear to your request when you need them the most.

在Senieer，我们为所有客户提供全面的瓶子支持。如果您需要安全的手来处理您在购买制药设备后经历的所有挑战，那么您就在与参赛者的正确位置。

Chapter 8: Cost and Shipping High Shear Mixer from China

The price of our Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator s varies based on the type and several other factors, such as process requirements and specifications.

然而，虽然参赛者可能不是中国的高剪切搅拌机的最便宜供应商，但是，您可以确定没有人为您提供比我们更好的资金bepaly娱乐投注价值。

If you are interested in making inquiries about the price of all our products, you can联系我们，请发送您的用户需求规范（URS），我们将为您提供反馈。

If you are shipping your Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator s from countries like Canada, the United States, South Korea, Thailand, Germany, Columbia, Egypt, Indonesia, Malaysia, Pakistan, Bangladesh, Turkey, Vietnam, etc. You can be sure that all our shipping processes will be taken care of expertly without you having to undergo any form of stress.

We shipSenieer productsare shipped via the sea and railway lines. The rail is used in countries that share proximity with China while sea freight is used for our customers ordering our products for long.

You can check这里to see all the processes involved in shipping high shear mixers and other machinery from china via sea freight.

Chapter 9: Frequently Asked Questions on Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator

如何快速混合器造粒机（RMG）或高剪切搅拌机造粒机的工作？bepaly娱乐投注

快速混合器造粒机（RMG）或高剪切搅拌机造粒机S.bepaly娱乐投注work by the forceful movement of two parts in opposite directions within the same plane to create a shear force. In a high shear mixer, the rotor circulates at high speed to propel materials outwardly directly to a stationary stator that carries out the actual shearing.

在高剪切混合器中使用的技术使得变化的转子速度允许bepaly娱乐投注混合设备获得纯粹的能量，这些能量将用于均匀化的固体或气体在没有高剪切混合器的帮助下不能达到的液体，这形成颗粒。

bepaly娱乐投注高剪切混合器用于分散，均质化，粒度减小和分散体。

How does a Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator compare to a high-pressure homogenizer?

High-pressure homogenizer engages a huge amount of energy to derive pressure needed to homogenize while high shear mixers make use of the actions of rotors and stators to derive particle size reduction.

我在哪里可以使用快速混合器造粒机（RMG）或高剪切搅拌机造粒机？bepaly娱乐投注

高剪bepaly娱乐投注切混合器均用于药品和胶囊等药品制造商的实验室。

高剪切混合器的实验室模型是什么？bepaly娱乐投注

It involves the use of laboratory high shear as a practical way to test the technology in need of liquid processing on different applications. It is a fast and convenient way for the R&D department to assess the formulation and processing strategies before embarking on scaled production.

How much does a high shear granulation cost?

您将花费在标准和质量快速混合器造粒机（RMG）或高剪切搅拌机造粒机上的钱取决于您需要的内容和加工应用。bepaly娱乐投注无论采购快速混合器造粒机（RMG）还是高剪切搅拌机造粒机所花费的量，您都可以放松，因为您必然会享受高度投资回报。bepaly娱乐投注它将通过缩短生产时间来帮助您节省时间。此外，它将提高您的整体生产力，并帮助您节省更多关于能源消耗和维护费用。如果您已准备好购买您的高剪切搅拌机和其他制药设备bepaly娱乐投注get in touchwith us and we will be glad to take yourorders.

Conclusion

快速混合器造粒机（RMG）或高剪切混合器造粒机bepaly娱乐投注is very useful equipment for both laboratory and industrial uses. Although there are probably hundreds of high shear mixer manufacturers and suppliers in China. However, you have been able to see for yourself that none can match the quality of products and services of Senieer Rapid Mixer Granulator (RMG) or High Shear Mixer Granulator.

If you are looking for a high shear mixer for sale in China and you want it shipped directly to use, feel free to get a free quick quotation from us right now.

Also, if you need any help on how to buy and get your high shear shipped to your doorstep, kindly接触Senieer now, and we will be glad to respond to you instantly.